001 — SL-2026-001

GHK-Cu

Copper Peptide Complex

GHK-Cu is one of the most studied peptides for skin rejuvenation and anti-aging. Naturally present in the body, its levels drop sharply after 30 — boosting collagen, speeding up wound healing, and supporting hair growth. Ready to use, no reconstitution needed.

✓ In Stock Injectable Solution 50 mg / vial Ready to Use COA Included
€44.90 €59.90
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SKUSL-GHKCU-50
FormInjectable Solution
Quantity50 mg / vial
Purity≥98% HPLC
CAS Number49557-75-7
Molecular FormulaC14H24CuN6O4
Molecular Weight340.38 g/mol
Storage2–8°C, protect from light
Shelf Life24 months (unopened)
ReconstitutionReady to use — no reconstitution required
Research Overview

What is GHK-Cu?

GHK-Cu is a naturally occurring copper peptide found in human plasma. Levels are high in your twenties — around 200 ng/mL — and decline to half that by age 60. This age-related drop has made GHK-Cu one of the most researched compounds in regenerative biology, with an unusually broad range of studied effects for such a small molecule.

The most documented effects are on collagen and elastin synthesis. GHK-Cu activates fibroblasts — the cells that produce the structural proteins keeping skin firm and elastic. Studies show significant upregulation of collagen production, improved skin thickness, and accelerated wound closure. Its gene-regulatory activity spans over 4,000 genes involved in tissue remodelling and inflammation resolution.

Beyond skin, GHK-Cu has been extensively studied for hair follicle stimulation — increasing follicle size, prolonging the growth phase, and improving scalp vascularisation. Sharp Labs supplies GHK-Cu as a ready-to-use injectable solution at ≥98% HPLC purity. No reconstitution required. Certificate of Analysis included with every order.

Research Applications

Studied mechanisms
in preclinical models.

Wound Healing & Tissue Repair
GHK-Cu has been consistently shown to accelerate wound closure in animal models through multiple mechanisms: stimulation of fibroblast proliferation and collagen synthesis, upregulation of MMP activity for tissue remodelling, and promotion of angiogenesis to restore blood supply to damaged tissue. Studies on excisional wound models show significantly accelerated re-epithelialisation and improved tissue organisation in treated subjects.
Anti-Inflammatory Research
The compound modulates cytokine activity with a well-characterised anti-inflammatory profile. It downregulates pro-inflammatory cytokines including TNF-α and IL-6 while reducing oxidative stress markers in cell culture models. Its copper coordination chemistry contributes to antioxidant activity through SOD-mimetic properties. This makes it a useful research tool for investigating inflammation-resolution pathways and the interplay between redox signalling and tissue repair.
Dermatology & Skin Biology
In dermatological research, GHK-Cu has been studied for its effects on elastin production, skin barrier function, and matrix metalloproteinase (MMP) regulation. Gene expression studies show upregulation of decorin, a proteoglycan involved in collagen fibril organisation. Research also documents effects on keratinocyte migration and proliferation, and reduced expression of pro-inflammatory molecules in UV-damaged skin models.
Hair Follicle Research
GHK-Cu has been investigated as a stimulant of hair follicle activity, with proposed mechanisms including increased follicle size, prolongation of the anagen (growth) phase, and upregulation of vascular supply to the follicle unit. In vitro models show effects on dermal papilla cell proliferation and IGF-1 expression. These properties make it a relevant compound for research into follicle biology and hair growth cycle modulation.
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